cas 86639 Search Results


cas  (Enamine Ltd)
90
Enamine Ltd cas
Cas, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cas/product/Enamine Ltd
Average 90 stars, based on 1 article reviews
cas - by Bioz Stars, 2026-02
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sn38  (Tocris)
94
Tocris sn38
Sn38, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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irinotecan active metabolite sn 38  (TargetMol)
93
TargetMol irinotecan active metabolite sn 38
Irinotecan Active Metabolite Sn 38, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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7-ethyl-10-hydroxycamptothecin (sn38, cas no. 86639-52-3)  (Millipore)
90
Millipore 7-ethyl-10-hydroxycamptothecin (sn38, cas no. 86639-52-3)
Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, <t> SN38 </t> and CAPE at different concentrations compared to untreated control cells.
7 Ethyl 10 Hydroxycamptothecin (Sn38, Cas No. 86639 52 3), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/7-ethyl-10-hydroxycamptothecin (sn38, cas no. 86639-52-3)/product/Millipore
Average 90 stars, based on 1 article reviews
7-ethyl-10-hydroxycamptothecin (sn38, cas no. 86639-52-3) - by Bioz Stars, 2026-02
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febuxostat (cas no. 86639-52-3)  (Millipore)
90
Millipore febuxostat (cas no. 86639-52-3)
Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, <t> SN38 </t> and CAPE at different concentrations compared to untreated control cells.
Febuxostat (Cas No. 86639 52 3), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/febuxostat (cas no. 86639-52-3)/product/Millipore
Average 90 stars, based on 1 article reviews
febuxostat (cas no. 86639-52-3) - by Bioz Stars, 2026-02
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cas 86639  (MedChemExpress)
95
MedChemExpress cas 86639
Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, <t> SN38 </t> and CAPE at different concentrations compared to untreated control cells.
Cas 86639, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cas 86639 52 3 gefitinib medchemexpress cat  (MedChemExpress)
95
MedChemExpress cas 86639 52 3 gefitinib medchemexpress cat
Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, <t> SN38 </t> and CAPE at different concentrations compared to untreated control cells.
Cas 86639 52 3 Gefitinib Medchemexpress Cat, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, SN38 and CAPE at different concentrations compared to untreated control cells.

Journal: Molecules

Article Title: Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro

doi: 10.3390/molecules25030658

Figure Lengend Snippet: Results of analysis of human cancer cell lines and peripheral blood lymphocytes viability after 72 h exposure to CPT-11, SN38 and CAPE at different concentrations compared to untreated control cells.

Article Snippet: Irinotecan hydrochloride trihydrate (CPT-11, CAS No. 100286-90-6), 7-Ethyl-10-hydroxycamptothecin (SN38, CAS No. 86639-52-3), DMSO (dimethyl sulfoxide), DAPI (4,6-diamidino-2-phenylindole), MTT [3(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], Histopaque 1077, were obtained from Sigma Chemicals Co. (St. Louis, MO, United States).

Techniques:

The effect of SN38 and co-treatment CAPE+SN38 on HCT116 cells ( A ), HT29 cells ( B ), AGS cells ( C ) and PBLs ( D ) growth after 72 h incubation evaluated by MTT assay (the mean ± SEM) Treatment of CAPE and SN38 simultaneously shows antagonistic effect on cytotoxicity of HT29, HCT116, AGS cells and PBLs. The figure under the graph show the ratio of expected cell number/observed cell number. Factor < 1 represents antagonistic effect CAPE on SN38.

Journal: Molecules

Article Title: Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro

doi: 10.3390/molecules25030658

Figure Lengend Snippet: The effect of SN38 and co-treatment CAPE+SN38 on HCT116 cells ( A ), HT29 cells ( B ), AGS cells ( C ) and PBLs ( D ) growth after 72 h incubation evaluated by MTT assay (the mean ± SEM) Treatment of CAPE and SN38 simultaneously shows antagonistic effect on cytotoxicity of HT29, HCT116, AGS cells and PBLs. The figure under the graph show the ratio of expected cell number/observed cell number. Factor < 1 represents antagonistic effect CAPE on SN38.

Article Snippet: Irinotecan hydrochloride trihydrate (CPT-11, CAS No. 100286-90-6), 7-Ethyl-10-hydroxycamptothecin (SN38, CAS No. 86639-52-3), DMSO (dimethyl sulfoxide), DAPI (4,6-diamidino-2-phenylindole), MTT [3(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], Histopaque 1077, were obtained from Sigma Chemicals Co. (St. Louis, MO, United States).

Techniques: Incubation, MTT Assay

Viability and caspase-3/7 activity after 24 h ( a ) and 72 h ( b ) of exposure on CAPE, CPT-11, CAPE + CPT-11, SN38 and CAPE + SN38 in AGS, HCT116 and HT29 cell line (mean ± S.E.M). * p < 0.05 as compared with control (untreated) cells; # p < 0.05 as compared with cells treated drug.

Journal: Molecules

Article Title: Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro

doi: 10.3390/molecules25030658

Figure Lengend Snippet: Viability and caspase-3/7 activity after 24 h ( a ) and 72 h ( b ) of exposure on CAPE, CPT-11, CAPE + CPT-11, SN38 and CAPE + SN38 in AGS, HCT116 and HT29 cell line (mean ± S.E.M). * p < 0.05 as compared with control (untreated) cells; # p < 0.05 as compared with cells treated drug.

Article Snippet: Irinotecan hydrochloride trihydrate (CPT-11, CAS No. 100286-90-6), 7-Ethyl-10-hydroxycamptothecin (SN38, CAS No. 86639-52-3), DMSO (dimethyl sulfoxide), DAPI (4,6-diamidino-2-phenylindole), MTT [3(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], Histopaque 1077, were obtained from Sigma Chemicals Co. (St. Louis, MO, United States).

Techniques: Activity Assay

DNA damage measured in HCT116 ( A ), HT29 ( B ), AGS ( C ) and PBLs ( D ) as the percentage of DNA in the comet tail in the alkaline version of comet assay incubated 24 h with CAPE in the presence of CPT-11 or SN38 (mean ± S.E.M). * p < 0.05 as compared with control (untreated) cells; # p < 0.05 as compared with cells treated drug.

Journal: Molecules

Article Title: Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro

doi: 10.3390/molecules25030658

Figure Lengend Snippet: DNA damage measured in HCT116 ( A ), HT29 ( B ), AGS ( C ) and PBLs ( D ) as the percentage of DNA in the comet tail in the alkaline version of comet assay incubated 24 h with CAPE in the presence of CPT-11 or SN38 (mean ± S.E.M). * p < 0.05 as compared with control (untreated) cells; # p < 0.05 as compared with cells treated drug.

Article Snippet: Irinotecan hydrochloride trihydrate (CPT-11, CAS No. 100286-90-6), 7-Ethyl-10-hydroxycamptothecin (SN38, CAS No. 86639-52-3), DMSO (dimethyl sulfoxide), DAPI (4,6-diamidino-2-phenylindole), MTT [3(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], Histopaque 1077, were obtained from Sigma Chemicals Co. (St. Louis, MO, United States).

Techniques: Single Cell Gel Electrophoresis, Incubation